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A highly driven, aspiring neuroscientist, exploring the scientific mysteries of the microbiota-gut-brain axis, elucidating its role in central and peripheral nervous system disorders, and developing innovative engineered live-biotherapeutics as therapeutics.
Microbes have harmoniously co-evolved with their host and developed a symbiotic bond that is essential in normal neurodevelopment, immune maturation and confers protection against foreign pathogens. They have been identified to modulate activity in the brain via various modalities of communication, and are found to be distinctly altered in individuals with neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
Since there is no cure for neurodegenerative diseases like Parkinson's and Alzheimer's Disease, developing innovative strategies to curtail the disease progression is critical. As a postdoctoral research associate in translational neuroscience at the Isakson Center for Neurological Disease Research, University of Georgia (UGA), my research involves developing novel microbiome-based therapeutics to deliver therapeutic molecules continuously, in a non-pulsatile manner. I utilize various molecular, analytical, and multi-omics tools to examine therapeutic efficacy in preclinical animal models of PD and AD. As a new mode of delivery, my goal is to limit the progression of Parkinson's and Alzheimer's disease and deliver clinical outcomes that will one day benefit patients and society.
What I Do...
Publications & Book Chapters
Patents
MICROENCAPSULATED AND CHROMOSOME INTEGRATED COMPOSITIONS FOR L-DOPA MICROBIOME THERAPY. https://uspto.report/patent/app/2022003177
MICROENCAPSULATED AND CHROMOSOME INTEGRATED COMPOSITIONS FOR L-DOPA MICROBIOME THERAPY. https://uspto.report/patent/app/2022003177
L-DOPA Microbiome Therapy:
https://patents.google.com/patent/US20230255915A1/en
L-DOPA Microbiome Therapy:
https://patents.google.com/patent/US20230255915A1/en
Invited Talks & Oral Presentations
Invited Talks & Oral Presentations
1. Infectious Disease Seminar Series - University of Georgia - Athens, GA, USA – September 8th, 2025
1. Infectious Disease Seminar Series - University of Georgia - Athens, GA, USA – September 8th, 2025
2. Neuroscience Seminar Series – University of Georgia - Athens, GA, USA – April 1st, 2025
2. Neuroscience Seminar Series – University of Georgia - Athens, GA, USA – April 1st, 2025
3. 4th Annual International Research Conference on Neurodegenerative Diseases– Atlanta, GA USA – July 16th-17th, 2024
3. 4th Annual International Research Conference on Neurodegenerative Diseases– Atlanta, GA USA – July 16th-17th, 2024
4. Southeast Regional Clinical & Translational Science Conference - Pine Mountain, GA, March 1st, 2023
4. Southeast Regional Clinical & Translational Science Conference - Pine Mountain, GA, March 1st, 2023
5. PCR Biotechnology Interest Group Seminar - National Institute of Health – Virtual, December 1st, 2022
5. PCR Biotechnology Interest Group Seminar - National Institute of Health – Virtual, December 1st, 2022
6. Microbiome Connect 2022 – Top Biotech Pitch Competition – Boston, MA, November 15th, 2022
6. Microbiome Connect 2022 – Top Biotech Pitch Competition – Boston, MA, November 15th, 2022
7. Bridging Centers Workshop - University of Georgia – Athens, GA, November 7th, 2022
7. Bridging Centers Workshop - University of Georgia – Athens, GA, November 7th, 2022
8. Division of Translational and Clinical Pharmacology – Young Investigators Awards Platform – ASPET at Experimental Biology, Philadelphia, PA, April 4th, 2022
8. Division of Translational and Clinical Pharmacology – Young Investigators Awards Platform – ASPET at Experimental Biology, Philadelphia, PA, April 4th, 2022
9. Trainee Award Winner Presentation - SfRBM – Neurodegeneration and Aging Thematic Symposium: SfRBM Annual Conference, Virtual, November 16th, 2021
9. Trainee Award Winner Presentation - SfRBM – Neurodegeneration and Aging Thematic Symposium: SfRBM Annual Conference, Virtual, November 16th, 2021
10. Biomedical Science Seminar Series - Department of Biomedical Sciences, Iowa State University, Ames, IA, March 24th, 2021
10. Biomedical Science Seminar Series - Department of Biomedical Sciences, Iowa State University, Ames, IA, March 24th, 2021
Skills & Trainings
Skills & Trainings
Analytical Techniques
High-Performance Liquid Chromatography
Electrochemical Detection
Liquid Chromatography-Mass Spectrometry - Targeted and Quantitative Metabolite Detection
Microbiology
Bacterial Cell Culture
Transformation and Restriction Digest
Gel Electrophoresis
Bioreactor Fermentation
Molecular Biology
Western Blotting
PCR (RT, qPCR, RT-qPCR)
Immunohistochemistry
Cell Culture
Animal Handling and Monitoring
Animal Behavior
Locomotor and Neuromuscular function Tests (Open Field, Gait, Pole, Rotarod, Grip Strength)
Dyskinesia Tests (Cylinder with AIMS scoring)
Depressive-like Tests (Forced Swim, Tail Suspension, Sucrose Preference)
Cognitive Tests (Morris Water Maze, Cued and Contextual Fear Conditioning, Y-maze)
Anxiety Tests (Elevated Plus, Open-Field)
Startle Test (pre-pulse inhibition)
Gut Functional Assays
Animal Surgery
Stereotaxic Surgery
Animal Necropsy and Tissue processing
Organ, Gut, Lymph Node Dissections
Brain microdissections
Perfusion and Fixation
Interests & Passions
Interests & Passions
HipHop/Bollywood Dancing:
Sports:
Martial Arts and Kickboxing: Brazilian Jiujitsu, Muay Thai, Jiujitsu, Krav Maga
Black Belt and Kickboxing Instructor for 10 years
Soccer and Basketball
"You cannot teach a man anything; you can only help him discover it in himself "
"You cannot teach a man anything; you can only help him discover it in himself "
Galileo Galilei
Galileo Galilei
Isakson Center for Neurological Disease Research
University of Georgia
500 D.W Brooks Drive, Athens, GA, 30602
Feel free to connect with me through email or social media links!
Feel free to connect with me through email or social media links!
Email: piyushpadhi@uga.edu
Email: piyushpadhi@uga.edu
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